Third-placed Arsenal tightened their grip on a spot in the top four on the English Premier League table, continuing an impressive run of form at the Emirates with a 3-0 win over West Ham United on Saturday.
Manchester City suffered their first home Premier League loss in eight months as a shock 3-2 defeat by Crystal Palace on Saturday left Pep Guardiola's champions trailing leaders Liverpool by four points.
Chelsea offered a chink of light to Manchester City in the Premier League title race after a stormy 1-1 home draw with Burnley on Saturday that gave more ammunition to their outspoken manager Jose Mourinho.
Chelsea put a miserable week behind them to return to the Premier League summit with a 2-0 win over Fulham as the wheels came off Liverpool's bright start in a 1-0 home defeat to Southampton on Saturday.
Tottenham Hotspur's exhilarating Premier League title surge came to a shuddering halt as they lost 1-0 at West Ham United on Friday to leave Chelsea needing six points from four games to be crowned champions.
Arsenal returned to the top of the Premier League on Sunday when they beat Crystal Palace 2-0 at the Emirates Stadium with both goals scored by Alex Oxlade-Chamberlain.
Liverpool had won each of their previous four home leagues games in which they conceded first and 12 minutes later they had turned another match on its head as Roberto Firmino's trickery set up Mane to give the hosts the lead at the second attempt.
IMAGES from the English Premier League matches played on Tuesday
Chelsea brought a whole new dimension to the Premier League title race when they handed Manchester City their first defeat of the season on Saturday to leave Mohamed Salah-inspired Liverpool as the new leaders.
Liverpool's boss paid tribute to the ace striker after he notched his 100th premier league goal.
Arsenal's Premier League title charge gathered momentum as they moved two points clear at the top with a scrappy 1-0 victory over Newcastle United on Saturday as Leicester City's push faltered with a goalless home draw against Bournemouth.
West Ham United manager Sam Allardyce believes it is acceptable for players to "make a meal out of" contact if it helps them win penalties and free kicks.
Leicester City were give a Premier League reality check when the unlikely leaders lost 1-0 at Liverpool on Saturday after Manchester United slumped to a third consecutive league defeat to pile more pressure on manager Louis van Gaal.
Second-half goals from Willian and Diego Costa helped Chelsea ease past Hull City 2-0 on Saturday and grab their first win in four Premier League games.
Thierry Henry's strike five minutes from time gave Arsenal a 2-1 victory at West Brom extending their lead to four points.\n\n
Images from the English Premier League matches played on Saturday
Tottenham Hotspur fluffed their last-day lines with a 5-1 defeat at relegated, 10-man Newcastle United that left them third in the Premier League behind bitter north London rivals Arsenal.
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Leicester City were left in touching distance of a fairytale first Premier League title on Sunday after Leonardo Ulloa's double helped them outclass Swansea City at a delirious King Power Stadium.
ManchesterCity moved up to third in the Premier League on Saturday while Newcastle United boosted their hopes of survival by coming back from two goals down at Liverpool to draw 2-2 and secure a precious point.
A downbeat Arsene Wenger said he has decided on his Arsenal future and would reveal all soon after his side slumped to a dismal 3-1 defeat at West Bromwich Albion on Saturday.
Chelsea surged to the top of the Premier League with a 3-0 home win over Stoke City thanks to goals from Mohamed Salah, Frank Lampard and Willian at Stamford Bridge on Saturday.
Chelsea's slim hopes of winning the Premier League all but evaporated in the Stamford Bridge sunshine on Sunday as Norwich City ground out a 0-0 draw that left them hanging on to top- flight status by their fingernails.
Belgium have retained injured Vincent Kompany in their final World Cup squad but put fellow defender Laurent Ciman on standby in case the Manchester City skipper is not fit for their opening match in Russia.
IMAGES from the English Premier League matches played on Saturday
Chelsea ripped apart Premier League title rivals Arsenal in a 6-0 mauling at Stamford Bridge on Saturday to ensure Arsene Wenger's 1,000th game turned sour and Liverpool and Manchester City kept up the pressure with big wins.
Cardiff had lost six of their previous seven games but, knowing that anything but a victory would probably end their survival hopes after one season in the top flight, overcame a strong Brighton start to play with growing confidence and fully deserved their victory.
League leaders Chelsea were made to battle for a narrow 2-1 win over strugglers Queens Park Rangers at Stamford Bridge as they maintained their unbeaten start in the Premier League on Saturday.
IMAGES from the English Premier League matches played on Wednesday.
Tottenham Hotspur's status as Premier League title chasers was seriously harmed on Saturday as they fell to a first defeat in seven league games, losing the lead to go down 3-1 at home to Wolverhampton Wanderers.
Sergio Aguero struck twice as Manchester City came from behind to beat Burnley 2-1 at Turf Moor in the Premier League on Saturday.
Arsenal sent Liverpool crashing out of the FA Cup, avenging last weekend's rout at Anfield, when they beat Brendan Rodgers's high-flyers 2-1 in a full-bloodied fifth round tie at the Emirates Stadium on Sunday.
Departing captain John Terry led his Chelsea champions to a rip-roaring 4-3 victory over Watford on Monday, scoring the first goal on an evening of celebration, fireworks and streamers rather than vintage football at Stamford Bridge.
Here are five talking points from the weekend's Premier League action:
Paolo Di Canio was forced out of Sunderland after a player revolt at the Italian's abrasive management style, media reported on Tuesday.
Antonio Conte spent the immediate aftermath of Chelsea's title-winning 1-0 victory at West Bromwich Albion on Friday being bounced skywards by his players but once back on terra firma his mind was already focusing on the next target -- the double.
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Nuggets of news coming from the English Premier League